The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2024
Filed:
Nov. 30, 2020
Applicant:
C4 Therapeutics, Inc., Watertown, MA (US);
Inventors:
Andrew J. Phillips, Arlington, VA (US);
Christopher G. Nasveschuk, Stoneham, MA (US);
James A. Henderson, Weston, MA (US);
Yanke Liang, Brookline, MA (US);
Minsheng He, Watertown, MA (US);
Kiel Lazarski, Watertown, MA (US);
Gesine Kerstin Veits, Watertown, MA (US);
Harit U. Vora, Watertown, MA (US);
Assignee:
C4 Therapeutics, Inc., Watertown, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/45 (2006.01); A61K 31/451 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 47/54 (2017.01); C07D 211/86 (2006.01); C07D 211/88 (2006.01); C07D 211/90 (2006.01); C07D 221/22 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 405/14 (2006.01); C07D 413/04 (2006.01); C07D 413/14 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 471/08 (2006.01); C07D 487/04 (2006.01); C07D 495/04 (2006.01); C07D 495/14 (2006.01); C07D 519/00 (2006.01); C07K 14/47 (2006.01); C07K 14/72 (2006.01);
U.S. Cl.
CPC ...
A61K 47/545 (2017.08); A61K 31/45 (2013.01); A61K 31/451 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); C07D 211/86 (2013.01); C07D 211/88 (2013.01); C07D 211/90 (2013.01); C07D 221/22 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 471/08 (2013.01); C07D 487/04 (2013.01); C07D 495/04 (2013.01); C07D 495/14 (2013.01); C07D 519/00 (2013.01); C07K 14/47 (2013.01); C07K 14/72 (2013.01);
Abstract
This invention provides Degronimers that have carbon-linked E3 Ubiquitin Ligase targeting moieties (Degrons), which can be linked to a targeting ligand for a protein that has been selected for in vivo degradation, and methods of use and compositions thereof as well as methods for their preparation.