The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2024
Filed:
Oct. 26, 2022
Applicant:
Lonza Sales Ag, Basel, CH;
Inventors:
Raymond J. Moniz, Brighton, MA (US);
Russell E. McConnell, Cambridge, MA (US);
Nikki Ross, Philadelphia, PA (US);
Christine McCoy, Cambridge, MA (US);
Timothy J. Soos, Boston, MA (US);
Ke Xu, Belmont, MA (US);
Assignee:
LONZA SALES AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); A61K 39/385 (2006.01); A61P 31/00 (2006.01); A61P 31/12 (2006.01); A61P 35/04 (2006.01); A61P 37/04 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/385 (2013.01); A61P 37/04 (2018.01); A61K 2039/60 (2013.01);
Abstract
The present disclosure relates to extracellular vesicles (EVs), e.g., exosomes, comprising a payload (e.g., an antigen, adjuvant, and/or immune modulator) and/or a targeting moiety. Also provided herein are methods for producing the EVs (e.g., exosomes) and methods for using the EVs (e.g., exosomes) to treat and/or prevent diseases or disorders, e.g., cancer, graft-versus-host disease (GvHD), autoimmune disease, infectious diseases, or fibrotic diseases.