The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2024
Filed:
Nov. 03, 2023
Applicant:
Academia Sinica, Taipei, TW;
Inventors:
Chi-Huey Wong, Taipei, TW;
Hsin-Yu Liao, New Taipei, TW;
Shih-Chi Wang, New Taipei, TW;
Yi-An Ko, Taipei, TW;
Kuo-I Lin, Taipei, TW;
Che Ma, New Taipei, TW;
Ting-Jen Cheng, New Taipei, TW;
Assignee:
ACADEMIA SINICA, Taipei, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/12 (2006.01); A61K 39/145 (2006.01); A61P 31/16 (2006.01); C07K 14/005 (2006.01);
U.S. Cl.
CPC ...
A61K 39/145 (2013.01); A61P 31/16 (2018.01); C07K 14/005 (2013.01); A61K 2039/575 (2013.01);
Abstract
The present disclosure relates to a chimeric influenza virus hemagglutinin (HA) polypeptide, comprising one or more stem domain sequence, each having at least 60% homology with a stem domain consensus sequence of H1 subtype HA (H1 HA) and/or H5 subtype HA (H5 HA), fused with one or more globular head domain sequence, each having at least 60% homology with a globular head domain consensus sequence of H1 subtype HA (H1 HA) or H5 subtype HA (H5 HA).