The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2024

Filed:

Oct. 28, 2015
Applicant:

Biovotec As, Oslo, NO;

Inventors:

Ralf Schmidt, Oslo, NO;

Henri-Pierre Suso, Oslo, NO;

Enda Kenny, Kilkenny, IE;

Assignee:

BIOVOTEC AS, Oslo, NO;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/57 (2015.01); A61K 9/14 (2006.01); A61L 15/40 (2006.01); A61L 15/60 (2006.01); A61L 26/00 (2006.01); A61L 27/36 (2006.01); A61L 31/00 (2006.01); A61L 31/08 (2006.01); A61P 17/02 (2006.01);
U.S. Cl.
CPC ...
A61K 35/57 (2013.01); A61K 9/14 (2013.01); A61L 15/40 (2013.01); A61L 15/60 (2013.01); A61L 26/0023 (2013.01); A61L 26/0057 (2013.01); A61L 26/008 (2013.01); A61L 27/3604 (2013.01); A61L 31/005 (2013.01); A61L 31/08 (2013.01); A61P 17/02 (2018.01); A61L 2300/30 (2013.01); A61L 2300/404 (2013.01); A61L 2300/41 (2013.01); A61L 2300/412 (2013.01);
Abstract

The invention provides a particle consisting essentially of micronized ESM and having a mean particle diameter of less than 100 μm for use in promoting the healing of a chronic wound at risk of, or in which there is, (i) an inappropriate level of matrix-metalloproteinase (MMP) activity against extracellular matrix (ECM) proteins and/or peptide growth or differentiation factors, and/or (ii) an excessive inflammatory response. The invention further provides pharmaceutical compositions, wound dressings and implantable medical devices comprising the micronized ESM-containing particles for use in said treatments. The invention still further provides methods for manufacturing the micronized ESM-containing particles and the compositions, dressings and implantable medical devices comprising the same.


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