The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2024

Filed:

Dec. 19, 2019
Applicants:

Abivax, Paris, FR;

Institut Curie, Paris, FR;

Universite DE Montpellier, Montpellier, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Inventors:

Philippe Pouletty, Paris, FR;

Hartmut Ehrlich, Paris, FR;

Didier Scherrer, Castelnau le Lez, FR;

Jamal Tazi, Clapiers, FR;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/706 (2006.01); A61P 1/16 (2006.01); A61P 9/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/706 (2013.01); A61P 1/16 (2018.01); A61P 9/12 (2018.01);
Abstract

A compound of Formula (I): or anyone of its metabolites or a pharmaceutically acceptable salt thereof, for use for treating and/or preventing an inflammatory disease, disorder or condition, wherein each R is independently hydrogen, halogen, —CN, hydroxyl, (C-C)fluoroalkyl, (C-C)fluoroalkoxy, (C-C)cycloalkyl, —NO, —NRR, (C-C)alkoxy, phenoxy, —NR—SO—NRR, —NR—SO—R1, —NR—C(═O)—R, —NR—C(═O)—NRR, —SO—NRR, —SOH, —O—SO—OR, —O—P(═O)—(OR)(OR), —O—CH—COOR, (C-C)alkyl; each R' is independently hydrogen, (C1-C3)alkyl, hydroxyl, halogen, —NO, —NRR, morpholinyl, morpholino, N-methylpiperazinyl, (C-C)fluoroalkyl, (C-C)alkoxy, —O—P(═O)—(OR)(OR), —CN, a —NH—SO—N(CH)group, or other groups and further relates to A compound of formula (IV): or a pharmaceutically acceptable salt thereof, for use for treating and/or preventing an inflammatory disease, disorder or condition, wherein V, Z, R, R', n, and n′ are as described above.


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