The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2024

Filed:

Mar. 15, 2023
Applicant:

Clexio Biosciences Ltd., Jerusalem, IL;

Inventors:

Derek Moe, Mound, MN (US);

Randal Seburg, Louisville, KY (US);

Sagar Rane, Bellevue, WA (US);

Assignee:

CLEXIO BIOSCIENCES LTD., Jersualem, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/135 (2006.01); A61K 9/20 (2006.01); G01N 30/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/135 (2013.01); A61K 9/2009 (2013.01); A61K 9/2013 (2013.01); A61K 9/2018 (2013.01); A61K 9/2027 (2013.01); A61K 9/2054 (2013.01); G01N 2030/027 (2013.01);
Abstract

Disclosed herein are immediate release oral dosage forms that contain abuse-deterrent and abuse-resistant features. In particular, the disclosed dosage forms can provide deterrence of abuse by ingestion of multiple individual doses. The disclosed dosage forms can likewise provide protection from overdose in the event of accidental or intentional ingestion of multiple individual doses. The dosage forms may also exhibit abuse resistant properties when physically manipulated, and also when physically manipulated and then administered in a manner not consistent with oral dosing. The dosage forms may also exhibit abuse resistant properties when administered in a manner intended to result in administration of the esketamine in a higher than therapeutic dose.


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