The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 21, 2024

Filed:

Jun. 11, 2021
Applicant:

Liposcience, Inc., Morrisville, NC (US);

Inventors:

James D. Otvos, Cary, NC (US);

Irina Y. Shalaurova, Cary, NC (US);

Assignee:

LipoScience, Inc., Morrisville, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); A61B 5/00 (2006.01); G01N 24/08 (2006.01); G01N 33/50 (2006.01); G01R 33/465 (2006.01); G16H 50/30 (2018.01); A61B 5/055 (2006.01);
U.S. Cl.
CPC ...
G16H 50/30 (2018.01); A61B 5/4842 (2013.01); A61B 5/7275 (2013.01); G01N 24/08 (2013.01); G01R 33/465 (2013.01); A61B 5/055 (2013.01);
Abstract

Methods, systems and circuits evaluate a subject's risk of developing type 2 diabetes using defined mathematical models of short term risk (STR) and longer term risk of progression. The evaluations can stratify risk for patients having the same glucose measurement, particularly those with intermediate or low (normal) fasting plasma glucose (FPG) values. The STR or IR (insulin resistance) model(s) may include an inflammatory biomarker such as an NMR derived measurements of GlycA and a plurality of selected lipoprotein components of at least one biosample of the subject. Embodiments of the invention also provide methods, systems and circuits that generate STR scores as a marker of beta-cell dysfunction or impairment.


Find Patent Forward Citations

Loading…