The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 21, 2024

Filed:

Mar. 29, 2018
Applicant:

Monsanto Technology Llc, St. Louis, MO (US);

Inventors:

David Vincent Butruille, Des Moines, IA (US);

Lex Evan Flagel, Arden Hills, MN (US);

Assignee:

Monsanto Technology LLC, Saint Louis, MO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G16B 20/00 (2019.01); A01H 1/04 (2006.01); C12N 15/82 (2006.01); C12Q 1/6895 (2018.01); G16B 20/50 (2019.01); G16B 40/00 (2019.01); G16B 20/20 (2019.01); G16B 25/00 (2019.01);
U.S. Cl.
CPC ...
G16B 20/00 (2019.02); A01H 1/04 (2013.01); C12N 15/8261 (2013.01); C12Q 1/6895 (2013.01); G16B 20/50 (2019.02); G16B 40/00 (2019.02); C12N 15/8243 (2013.01); Y02A 40/146 (2018.01);
Abstract

Exemplary systems and methods for selecting from population of candidate edits and predicting an aggregate effect of the candidate edits are disclosed. One exemplary method includes identifying a population of candidate edits to a genomic sequence of said organism and ranking each of the candidate edits based on a predicted ability of each candidate edit to affect a trait of interest in said organism. The exemplary method further includes selecting one or more of the candidate edits based on the ranking and predicting, by the computing device, an aggregate effect of the selected one or more of the candidate edits for the trait of interest when expressed by a specimen of the organism having a genomic sequence and edited according to the selected one or more of the candidate edits, as compared to an unedited specimen of the organism.


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