The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2024
Filed:
Apr. 02, 2019
Applicant:
Korea University Research and Business Foundation, Seoul, KR;
Inventors:
Byoung Soo Kim, Seoul, KR;
Seung Jin Lee, Seoul, KR;
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/074 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0696 (2013.01); C12N 2501/604 (2013.01); C12N 2501/606 (2013.01); C12N 2501/998 (2013.01); C12N 2502/025 (2013.01); C12N 2506/025 (2013.01); C12N 2506/28 (2013.01); C12N 2533/54 (2013.01);
Abstract
The present invention relates to a composition for inducing dedifferentiation form somatic cells to induced pluripotent stem cells (iPSs) and method of inducing dedifferentiation using same, wherein the composition for inducing dedifferentiation and the method of inducing dedifferentiation increases the efficiency of dedifferentiation from somatic cells to iPSs by stimulating CXC chemokine receptor 2 (CXCR2), which is a receptor on human somatic cells, and thus may be effectively used for inducing the dedifferentiation to iPSs.