logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11987805 B1

PDFFull Text
Date of Patent:
May. 21, 2024

Filed:

Sep. 24, 2021

Attb cell line, transgenic cell lines derived therefrom, and methods of making the same

Applicant:

Albert Einstein College of Medicine, Bronx, NY (US);

Inventors:

William R. Jacobs, Jr., Bronx, NY (US);

Lawrence Leung, Flushing, NY (US);

Regy Lukose, Flanders, NJ (US);

Anna Paula de Oliveira, Bronx, NY (US);

Assignee:

ALBERT EINSTEIN COLLEGE OF MEDICINE, Bronx, NY (US);

Attorney:

CANTOR COLBURN LLP

Primary Examiner:

Nianxiang Zou

Int. Cl.
CPC ...
C12N 15/01 (2006.01); C07K 14/35 (2006.01); C12N 7/00 (2006.01); C12N 9/22 (2006.01); C12N 15/09 (2006.01); C12N 15/11 (2006.01); C12N 15/90 (2006.01); C12Q 1/70 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C07K 14/35 (2013.01); C12N 7/00 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12Q 1/70 (2013.01); C12N 2310/20 (2017.05); C12N 2710/16652 (2013.01); C12N 2800/80 (2013.01);
Abstract

A genetically modified mammalian cell and genetically modified mammalian cell line comprise a recombination sequence inserted in a target locus on a chromosome of the mammalian cell genome, wherein the recombination sequence comprises Bxb1attB sequence from. A transgenic mammalian cell and transgenic mammalian cell line comprise a heterologous nucleic acid stably integrated in a target locus on a chromosome of the mammalian genome, wherein the heterologous nucleic comprises a heterologous gene configured for expression by the transgenic mammalian cell.

Find Patent Forward Citations

Loading…