The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2024
Filed:
Oct. 17, 2018
Massachusetts Institute of Technology, Cambridge, MA (US);
Beth Israel Deaconess Medical Center, Boston, MA (US);
Melina Claussnitzer, Boston, MA (US);
Liang He, Cambridge, MA (US);
Manolis Kellis, Cambridge, MA (US);
Xinchen Wang, Cambridge, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Beth Israel Deaconess Medical Center, Boston, MA (US);
Abstract
Embodiments disclosed herein provide a general, scalable, high-throughput, and high-resolution approach for experimental dissection of regulatory regions and driver nucleotides in the context of human biology and disease. Applicants present HiDRA, a novel high-resolution global screen for transcriptional regulatory activity in accessible chromatin regions, enabling high-efficiency, high-throughput, and high-resolution inference of regulatory activity.