The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2024
Filed:
Dec. 17, 2020
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Tina Weinzierl, Remetschwil, CH;
Lydia Jasmin Hanisch, Birmensdorf, CH;
Alexander Bujotzek, Munich, DE;
Alejandro Carpy Gutierrez Cirlos, Munich, DE;
Stefan Klostermann, Neuried, DE;
Christian Klein, Bonstetten, CH;
Simon Patrick Keiser, Aarau, CH;
Tanja Fauti, Zurich, CH;
Estelle Marrer-Berger, Basel, CH;
Pablo Umaña, Wollerau, CH;
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Abstract
The present invention generally relates to antibodies that bind to HLA-A2/MAGE-A4, including multispecific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.