The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 21, 2024

Filed:

Feb. 04, 2021
Applicants:

Ethicon, Inc., Somerville, NJ (US);

Omrix Biopharmaceuticals Ltd., Rehovot, IL;

Inventors:

James Galloway, Bridgewater, NJ (US);

Tamara Byk-Tennenbaum, Kiryat Ono, IL;

Erez Ilan, Kibbutz Netzer Sereni, IL;

Lior Weissman, Nes-Ziona, IL;

Sivan Doron, Moshav Arugot, IL;

Eve Montia, Rehovot, IL;

Assignees:

Ethicon, Inc., Raritan, NJ (US);

Omrix Biopharmaceuticals Ltd., Kiryat Ono, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/717 (2006.01); A61K 31/704 (2006.01); A61L 15/28 (2006.01); A61L 15/44 (2006.01); A61L 24/00 (2006.01); A61L 24/08 (2006.01);
U.S. Cl.
CPC ...
A61K 31/717 (2013.01); A61K 31/704 (2013.01); A61L 15/28 (2013.01); A61L 15/44 (2013.01); A61L 24/0015 (2013.01); A61L 24/0042 (2013.01); A61L 24/08 (2013.01); A61L 2400/04 (2013.01);
Abstract

The present invention is directed to methods of enhancing toxicity of a glycolytic dependent compound towards a cancerous tissue and/or organ in a subject, the method being comprised of targeting the glycolytic dependent compound to the cancerous tissue and/or organ by placing oxidized regenerated cellulose (ORC) and/or oxidized cellulose (OC) in direct connection with the cancerous tissue and/or organ, and administering the glycolytic dependent compound to the subject by a systemic route.


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