The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2024
Filed:
Feb. 02, 2018
Applicant:
Tohoku University, Sendai, JP;
Inventors:
Hirokazu Arimoto, Sendai, JP;
Kaori Itto, Sendai, JP;
Daiki Takahashi, Sendai, JP;
Nobuo Cho, Fujisawa, JP;
Hiroshi Nara, Fujisawa, JP;
Kenichiro Shimokawa, Fijisawa, JP;
Taiichi Ohra, Fujisawa, JP;
Shigekazu Sasaki, Fujisawa, JP;
Naoki Ishii, Fujisawa, JP;
Assignee:
TOHOKU UNIVERSITY, Miyagi, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); A61K 31/513 (2006.01); A61K 31/522 (2006.01); A61K 31/551 (2006.01);
U.S. Cl.
CPC ...
A61K 31/522 (2013.01); A61K 31/513 (2013.01); A61K 31/551 (2013.01); C07D 495/04 (2013.01);
Abstract
Provided is a novel compound or salt thereof that induces degradation by autophagy of an intracellular molecule. In this compound, a ligand having activity to bind to an intracellular molecule and a structure having activity to induce autophagy of an intracellular molecule are linked via a linker without loss of the activity of the ligand and the structure.