The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2024
Filed:
Dec. 27, 2018
Applicant:
Takeda Pharmaceutical Company Limited, Osaka, JP;
Inventors:
Assignee:
TAKEDA PHARMACEUTICAL COMPANY LIMITED, Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/435 (2006.01); A61K 38/00 (2006.01); B01D 15/16 (2006.01); B01D 15/36 (2006.01); B01D 15/38 (2006.01); B01D 15/42 (2006.01); C07K 14/705 (2006.01); C07K 16/28 (2006.01); C12N 7/00 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); B01D 15/166 (2013.01); B01D 15/363 (2013.01); B01D 15/3809 (2013.01); B01D 15/426 (2013.01); G01N 33/56983 (2013.01); C12N 2750/14151 (2013.01); G01N 2333/075 (2013.01);
Abstract
Provided herein are methods of producing an adeno-associated virus (AAV) product and methods of purifying adeno-associated virus. AAV is loaded onto an affinity resin, wash steps are undertaken, and AAV is eluted from the affinity resin. Various buffers are disclosed for use in the wash steps and elution.