The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2024

Filed:

Jun. 06, 2022
Applicant:

Ethris Gmbh, Planegg, DE;

Inventors:

Christian Plank, Wessling, DE;

Carsten Rudolph, Krailling, DE;

Manish Kumar Aneja, Munich, DE;

Ludwig Weiss, Kissing, DE;

Assignee:

ethris GmbH, Planegg, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 5/071 (2010.01); C12N 15/67 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); C12N 5/0688 (2013.01); C12N 15/113 (2013.01); C12N 15/67 (2013.01); C12N 2015/8572 (2013.01); C12N 2015/859 (2013.01); C12N 2800/107 (2013.01); C12N 2800/22 (2013.01); C12N 2830/34 (2013.01); C12N 2840/105 (2013.01);
Abstract

Described are DNA molecules which can be transcribed into an mRNA harbouring novel UTR sequences combining the advantages of being extremely short and at the same time allowing for high translation efficiencies of RNA molecules containing them. Further, described are vectors comprising such a DNA molecule and to host cells comprising such a vector. Moreover, described are corresponding RNA molecules containing such UTRs. Further, described is a pharmaceutical composition comprising the described RNA molecule and optionally a pharmaceutically acceptable carrier as well as to the use of the described UTRs for translating a coding region of an RNA molecule into a polypeptide or a protein encoded by said coding region.


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