The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2024
Filed:
Jun. 28, 2023
Applicant:
1e Therapeutics Ltd., Rehovot, IL;
Inventors:
Noam Pilpel, Rehovot, IL;
Yossi Ovadya, Rehovot, IL;
Dina Raichlin, Rehovot, IL;
Etti Katz-Kadosh, Rehovot, IL;
Alaa Knany, Rehovot, IL;
Ella Gillis, Rehovot, IL;
Noam Borovsky, Rehovot, IL;
Anastasia Shapiro, Rehovot, IL;
Ido Bachelet, Rehovot, IL;
Assignee:
1E Therapeutics Ltd., Rehovot, IL;
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61P 35/00 (2018.01); C12N 2310/14 (2013.01); C12N 2310/32 (2013.01);
Abstract
Compositions of matter comprising RNA silencing molecules capable of mediating cleavage of p21 mRNA are disclosed. Methods of eradicating senescent cells or cancer cells, as well as methods of treating senescence-associated diseases or disorders, cancer, and fibrotic diseases and disorders are also disclosed.