The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2024

Filed:

Jun. 28, 2019
Applicants:

The Regents of the University of Colorado, Denver, CO (US);

University of New Hampshire, Durham, NH (US);

Inventors:

Jung-Jae Lee, Aurora, CO (US);

Kyung Jae Jeong, Durham, NH (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C08F 20/40 (2006.01); A61K 9/00 (2006.01); A61P 27/02 (2006.01); C07D 213/38 (2006.01); C08J 3/075 (2006.01);
U.S. Cl.
CPC ...
C08F 20/40 (2013.01); A61K 9/0051 (2013.01); A61P 27/02 (2018.01); C07D 213/38 (2013.01); C08J 3/075 (2013.01); C08J 2333/14 (2013.01);
Abstract

The present invention relates to the unexpected discovery of a cross-linked polymer of 2-hydroxyethyl methacrylate and dipicolylamine-containing monomers that can be used as a therapeutic lens to treat ocular diseases or disorders associated with matrix metalloproteinase (MMP) over-activity and/or over-expression, such as but not limited to corneal melting (or keratolysis).


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