The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2024
Filed:
May. 01, 2018
Applicant:
Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA (US);
Inventors:
Hongbo Pang, La Jolla, CA (US);
Erkki Ruoslahti, La Jolla, CA (US);
Assignee:
Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/04 (2006.01); A61K 47/69 (2017.01); C07K 7/06 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); A61K 47/6911 (2017.08); A61K 38/00 (2013.01);
Abstract
Disclosed are compositions and methods useful for targeting molecules to activated macrophages, such as tumor associated macrophages. The compositions and methods are based on peptide sequences, such as AMT peptides, that home to activated macrophages. The disclosed homing to activated macrophages is useful for delivering therapeutic and detectable agents to cells and tissues where immune system effects or inflammation are occurring.