The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2024
Filed:
Nov. 13, 2020
Applicants:
Stcube, Inc., Seoul, KR;
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Stephen S. Yoo, Centreville, VA (US);
Ezra M. Chung, North Potomac, MD (US);
Yong-Soo Kim, Rockville, MD (US);
Seung-Oe Lim, Houston, TX (US);
Chia-Wei Li, Houston, TX (US);
Mien-Chie Hung, Houston, TX (US);
Assignees:
ST CUBE INC., Seoul, KR;
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61K 9/00 (2006.01); A61K 39/395 (2006.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); C07K 16/44 (2006.01); C12N 5/20 (2006.01); C12N 15/00 (2006.01); C12N 15/87 (2006.01); C12P 21/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2818 (2013.01); A61K 9/0019 (2013.01); A61K 39/395 (2013.01); A61K 47/6849 (2017.08); A61P 35/00 (2018.01); C07K 16/18 (2013.01); C07K 16/28 (2013.01); C07K 16/44 (2013.01); C07K 2317/34 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract
Antibodies that selectively bind to glycosylated PD-1 relative to unglycosylated PD-1 are provided. In some aspects, PD-1 polypeptides comprising glycosylated amino acid positions are also provided. Methods for making and using such antibodies and polypeptides (e.g., for the treatment of cancer) are also provided.