The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2024

Filed:

Dec. 13, 2022
Applicant:

Merck Sharp & Dohme Llc, Rahway, NJ (US);

Inventors:

Kalpit A. Vora, Yardley, PA (US);

Kara S. Cox, Harleysville, PA (US);

Aimin Tang, Lansdale, PA (US);

Zhifeng Chen, Warrington, PA (US);

Daniel DiStefano, Harleysville, PA (US);

Lan Zhang, Chalfont, PA (US);

Hua-Poo Su, Phoenixville, PA (US);

Assignee:

Merck Sharp & Dohme LLC, Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); A61K 39/00 (2006.01); A61K 39/42 (2006.01); A61P 31/14 (2006.01); C07K 14/005 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1027 (2013.01); A61K 39/42 (2013.01); A61P 31/14 (2018.01); A61K 2039/505 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01); C07K 2317/14 (2013.01); C07K 2317/21 (2013.01); C07K 2317/34 (2013.01); C07K 2317/41 (2013.01); C07K 2317/524 (2013.01); C07K 2317/565 (2013.01); C07K 2317/732 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

The present invention relates to monoclonal antibodies which have high anti-RSV neutralizing titers. The invention further provides for isolated nucleic acids encoding the antibodies of the invention and host cells transformed therewith. The invention yet further provides for diagnostic, prophylactic and therapeutic methods employing the antibodies and nucleic acids of the invention, particularly as a passive immunotherapy agent in infants and the elderly.


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