The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2024

Filed:

Jan. 06, 2023
Applicant:

Flagship Pioneering Innovations Vi, Llc, Cambridge, MA (US);

Inventors:

Gevorg Grigoryan, Arlington, MA (US);

John Ingraham, Cambridge, MA (US);

Cheuk Lun Leung, Quincy, MA (US);

Ross Steven Federman, Dorchester, MA (US);

Robin Jeffrey Green, Cambridge, MA (US);

Alexis Hiram Ramos, Cambridge, MA (US);

Jenhan Tao, Cambridge, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); A61P 31/14 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/10 (2013.01); A61P 31/14 (2018.01); A61K 39/00 (2013.01); C07K 2317/52 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01);
Abstract

The invention provides, in various embodiments, polypeptides that specifically bind to Spike glycoprotein of severe acute respiratory syndrome coronavirus (e.g., SARS-CoV-2-Spike). The invention also provides, in various embodiments, fusion proteins comprising one or more of the polypeptides, polynucleotides encoding the polypeptides, vectors and host cells suitable for expressing the polypeptides, and methods for treating viral infections (e.g., COVID-19).


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