The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2024

Filed:

May. 27, 2020
Applicant:

Ampsource Biopharma Shanghai Inc., Shanghai, CN;

Inventors:

Zhao Dong, Shanghai, CN;

Chi Zhou, Shanghai, CN;

Xiong Feng, Shanghai, CN;

Jiyu Zhang, Shanghai, CN;

Shixiang Jia, Shanghai, CN;

Qiang Li, Shanghai, CN;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/26 (2006.01); A61K 38/18 (2006.01); C07K 14/50 (2006.01); C07K 14/605 (2006.01); C12N 15/85 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/605 (2013.01); C07K 14/50 (2013.01); C12N 15/85 (2013.01); A61K 38/00 (2013.01);
Abstract

The present disclosure relates to a dual-function protein for regulating blood glucose and lipid metabolism, wherein said dual-function protein comprises a human GLP-1 analog and human FGF21. In the present disclosure, provided is a method for preparing said dual function protein, and also provided is the use of said dual-function protein in the preparation of a biological substance for treating type 2 diabetes, obesity, dyslipidemia, fatty liver disease and/or metabolic syndrome. The dual-function protein provided in the present disclosure can synergistically regulate blood glucose and lipid levels in vivo, and satisfy multiple requirements for patients with type 2 diabetes such as lowering blood glucose, relieving hepatic steatosis, reducing body weight and improving metabolic disorders of circulating lipids.


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