The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2024

Filed:

Mar. 14, 2019
Applicant:

Pfizer Inc., New York, NY (US);

Inventors:

Tamim Fehme Braish, Groton, CT (US);

Matthew Frank Brown, Stonington, CT (US);

Ye Che, Niantic, CT (US);

Richard Andrew Ewin, Kalamazoo, MI (US);

Timothy Allan Johnson, Vicksburg, MI (US);

Michael Joseph Melnick, Portage, MI (US);

Justin Ian Montgomery, Ledyard, CT (US);

Mark Stephen Plummer, Westbrook, CT (US);

Loren Michael Price, Pensacola, FL (US);

Usa Reilly, New Haven, CT (US);

Daniel Uccello, Colchester, CT (US);

Assignee:

Pfizer Inc., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/58 (2006.01); A61P 31/04 (2006.01); C07F 5/02 (2006.01);
U.S. Cl.
CPC ...
C07F 9/58 (2013.01); A61P 31/04 (2018.01); C07F 5/022 (2013.01);
Abstract

The present invention is directed to a new fluoro-pyridinone hydroxamic acid phosphates and boronates of Formulae I, II and III wherein Q is selected from the group consisting of —P(O)(OH), —P(O)(OH)(OM), —P(O)(OM)and —P(O)(O)M; Mat each occurrence is a pharmaceutically acceptable monovalent cation; and Mis a pharmaceutically acceptable divalent cation and their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.


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