The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2024

Filed:

Nov. 05, 2021
Applicant:

Cytokinetics, Inc., South San Francisco, CA (US);

Inventors:

Bradley P. Morgan, South San Francisco, CA (US);

Chris Evans, South San Francisco, CA (US);

Pu-Ping Lu, South San Francisco, CA (US);

Makoto Yamasaki, South San Francisco, CA (US);

Wenyue Wang, South San Francsco, CA (US);

Scott Collibee, South San Francisco, CA (US);

Takuya Makino, Tokyo, JP;

Kazuyuki Tsuchiya, Tokyo, JP;

Toshio Kurosaki, Tokyo, JP;

Susumu Yamaki, Tokyo, JP;

Eriko Honjo, Tokyo, JP;

Yuka Koizumi, Tokyo, JP;

Naoto Katoh, Tokyo, JP;

Ryuichi Sekioka, Tokyo, JP;

Ikumi Kuriwaki, Tokyo, JP;

Assignee:

CYTOKINETICS, INC., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 243/14 (2006.01); C07D 401/12 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 413/08 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 471/04 (2006.01); C07D 471/10 (2006.01); C07D 487/04 (2006.01); C07D 498/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 243/14 (2013.01); C07D 401/12 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 413/08 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 471/10 (2013.01); C07D 487/04 (2013.01); C07D 498/04 (2013.01); C07D 519/00 (2013.01); C07B 2200/13 (2013.01);
Abstract

Provided herein are compounds of formula (1): or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein X, X, R, R, R, R, R, and Rare as defined herein. Also provided herein is a pharmaceutically acceptable composition comprising a compound of formula (I), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing. Also provided herein are methods of using a compound of formula (I), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, to treat various diseases, disorders, and conditions responsive to the modulation of the contractility of the skeletal sarcomere.


Find Patent Forward Citations

Loading…