The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2024

Filed:

Dec. 01, 2020
Applicant:

International Business Machines Corporation, Armonk, NY (US);

Inventors:

Robert Dean Lovchik, Schoenenberg, CH;

Anna Fomitcheva Khartchenko, Zurich, CH;

Iago Pereiro Pereiro, Zurich, CH;

Lorenzo Franco Teodoro Petrini, Verscio, CH;

Govind Kaigala, Rueschlikon, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/50855 (2013.01); B01L 3/50273 (2013.01); B01L 2200/10 (2013.01); B01L 2400/049 (2013.01);
Abstract

A microtiter plate comprising a first array of M×N wells and a microfluidic probe insert is provided. The microfluidic probe insert includes a second array of M×N microfluidic probe conduits, forming N columns of M conduits. The M conduits include respective orifices in a bounding plane and extend, each, perpendicularly to the bounding plane on one side. The microfluidic probe insert also includes N vacuum circuits, each comprising at least one vacuum port and M openings in the bounding plane, where 2≤M, 2≤N. The microfluidic probe insert is positioned on the microtiter plate and the microfluidic probe conduits are inserted in respective wells. A processing liquid is ejected from M conduits via the M orifices of the M conduits by applying a negative pressure to a corresponding set of N vacuum circuits via the respective one or more vacuum ports.


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