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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11980652 B1

PDFFull Text
Date of Patent:
May. 14, 2024

Filed:

Jan. 04, 2022

Compositions and methods for subcutaneous administration of cancer immunotherapy

Applicant:

Mural Oncology, Inc., Waltham, MA (US);

Inventors:

Heather C. Losey, Lexington, MA (US);

Jared Lopes, Wilmington, MA (US);

Lei Sun, Waltham, MA (US);

Raymond J. Winquist, Marshfield, MA (US);

Assignee:

Mural Oncology, Inc., Waltham, MA (US);

Attorney:

Fish & Richardson P.C.

Primary Examiner:

Jeanette M Lieb

Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 9/00 (2006.01); A61K 38/16 (2006.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 38/16 (2013.01); A61K 9/0019 (2013.01); A61K 39/3955 (2013.01); A61P 35/00 (2018.01); C07K 16/2818 (2013.01);
Abstract

The invention provides compositions, methods and treatment regimens for treating cancer comprising periodic subcutaneous administration of the fusion protein of SEQ ID NO:1 to a cancer patient resulting in enhanced activation of CD8+ T-cells with minimal effects on regulatory T cell (T) expansion and providing enhanced anti-tumor efficacy while also mitigating T cell inactivation/exhaustion.

Find Patent Forward Citations

Losey, Heather. (2024). Compositions and methods for subcutaneous administration of cancer immunotherapy (U.S. Patent No. 11980652). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11980652

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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