The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2024
Filed:
Jul. 29, 2019
The Johns Hopkins University, Baltimore, MD (US);
Rensselaer Polytechnic Institute, Troy, NY (US);
Andres Hurtado, Baltimore, MD (US);
Ryan James Gilbert, Houghton, MI (US);
Han Bing Wang, Houghton, MI (US);
Jared M. Cregg, Houghton, MI (US);
Michael E. Mullins, Houghton, MI (US);
Martin Oudega, Munhall, PA (US);
Rensselaer Polytechnic Institute, Troy, NY (US);
Johns Hopkins University, Baltimore, MD (US);
Abstract
One aspect of the invention provides a three-dimensional scaffold including at least one layer of highly-aligned fibers. The at least one layer of highly-aligned fibers is curved in a direction substantially perpendicular to a general direction of the fibers. Another aspect of the invention provides a method for fabricating a three-dimensional scaffold. The method includes: electro spinning a plurality of fibers to produce at least one layer of highly-aligned fibers and forming the at least one layer of highly-aligned fibers into a three-dimensional scaffold without disturbing the alignment of the highly-aligned polymer fibers. A further aspect of the invention provides methods for using a three-dimensional scaffold to treat nerve or spinal cord injury.