The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 07, 2024

Filed:

Dec. 13, 2018
Applicant:

Rappaport Family Institute for Research IN the Medical Sciences, Haifa, IL;

Inventor:

Yuval Shaked, Binyamina, IL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); A61P 35/00 (2006.01); C07K 16/00 (2006.01); C07K 16/24 (2006.01); C07K 16/28 (2006.01); G01N 33/577 (2006.01); G01N 33/68 (2006.01); G01N 33/74 (2006.01); G06F 17/15 (2006.01); G16B 5/00 (2019.01); G16B 25/10 (2019.01); G16H 50/20 (2018.01); G16H 50/30 (2018.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/574 (2013.01); A61P 35/00 (2018.01); C07K 16/00 (2013.01); C07K 16/248 (2013.01); C07K 16/2803 (2013.01); C07K 16/2818 (2013.01); C07K 16/2878 (2013.01); G01N 33/577 (2013.01); G01N 33/6857 (2013.01); G01N 33/74 (2013.01); G06F 17/15 (2013.01); G16B 5/00 (2019.02); G16B 25/10 (2019.02); G16H 50/20 (2018.01); G16H 50/30 (2018.01); A61K 2039/505 (2013.01); G01N 2800/52 (2013.01);
Abstract

A method and a kit are provided for predicting a favorable or a non-favorable response of a cancer patient to treatment with an immune checkpoint inhibitor by determining in a biological sample obtained from the cancer patient, before and after the treatment, the changes of the levels of factors/biomarkers generated by the cancer patient in response to said treatment, and a method for treatment of a cancer patient with an immune checkpoint inhibitor.


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