The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2024
Filed:
Jan. 27, 2021
Applicant:
Bioatla, Inc,., San Diego, CA (US);
Inventor:
Jay Milton Short, Jackson, WY (US);
Assignee:
BioAtla, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 30/04 (2006.01); C07K 16/00 (2006.01); C12N 15/10 (2006.01); C40B 50/06 (2006.01);
U.S. Cl.
CPC ...
C40B 30/04 (2013.01); C07K 16/00 (2013.01); C12N 15/1058 (2013.01); C40B 50/06 (2013.01); C07K 2317/21 (2013.01); C07K 2317/52 (2013.01);
Abstract
The present disclosure provides methods of integrating therapeutic protein and antibody generation and/or selection, evolution and expression in a eukaryotic host for manufacturing in a single system. Therapeutic proteins, including antibodies, are generated, optimized and manufactured in the same eukaryotic host system. The disclosed system of Comprehensive Integrated Antibody Optimization (CIAO!™) allows for simultaneous evolution of protein performance and expression optimization.