The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2024
Filed:
Mar. 19, 2018
Astrego Diagnostics Ab, Uppsala, SE;
Johan Elf, Uppsala, SE;
Michael Read, Uppsala, SE;
Özden Baltekin, Uppsala, SE;
Martin Lovmar, Mölndal, SE;
Petter Hammar, Årsta, SE;
Elias Amselem, Stockholm, SE;
Mikael Olsson, Uppsala, SE;
Ove Öhman, Uppsala, SE;
ASTREGO DIAGNOSTICS AB, Uppsala, SE;
Abstract
Phenotyping of cells involves loading a biological sample into a microfluidic device () comprising cell compartments () to capture biological material, including target cells, in the sample in the cell compartments (). A subset (A) of the cell compartments () is identified as comprising target cells exhibiting target phenotype characteristic(s) as determined based on monitoring biological material in the cell compartments () prior to addition of a test agent. The biological material is exposed to a test agent and a phenotypic response of the target cells to the test agent is determined based on monitoring target cells in the identified subset (A) of the cell compartments (). The phenotyping of the target cells is thereby not overshadowed by the response of other cells and non-cell material present in the biological sample.