The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2024
Filed:
Mar. 22, 2021
Applicants:
Megakaryon Corporation, Kyoto, JP;
Kyoto University, Kyoto, JP;
Inventors:
Takeaki Dohda, Kyoto, JP;
Sachiko Kobayashi, Kyoto, JP;
Koji Eto, Kyoto, JP;
Hiroshi Endo, Kyoto, JP;
Sou Nakamura, Kyoto, JP;
Assignees:
Megakaryon Corporation, Kyoto, JP;
Kyoto University, Kyoto, JP;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/078 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0644 (2013.01); C12N 2500/25 (2013.01); C12N 2500/38 (2013.01); C12N 2501/125 (2013.01); C12N 2501/145 (2013.01); C12N 2501/727 (2013.01); C12N 2501/998 (2013.01); C12N 2506/45 (2013.01); C12N 2510/00 (2013.01);
Abstract
The present invention provides a method for producing megakaryocytes that have an increased capacity to produce platelets, the method comprising a step of culturing, under conditions that cause the death of cells that do not express a gene that is specifically expressed by megakaryocytes, cells that have the capacity to differentiate into megakaryocytes.