The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2024
Filed:
Dec. 31, 2018
Applicant:
The U.s.a., As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Inventors:
Nancy Sullivan, Kensington, MD (US);
Kendra Leigh, Frankfurt am Main, DE;
John Misasi, Kensington, MD (US);
Alberto Cagigi, Stockholm, SE;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); A61K 39/00 (2006.01); A61K 48/00 (2006.01); A61P 31/14 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
C07K 16/10 (2013.01); A61P 31/14 (2018.01); G01N 33/56983 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); A61K 48/005 (2013.01); C07K 2317/33 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/72 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); G01N 2333/08 (2013.01); G01N 2400/02 (2013.01); G01N 2469/10 (2013.01);
Abstract
Antibodies and antigen binding fragments that specifically bind to ebolavirus glycoprotein and neutralize ebolavirus infection are disclosed. Nucleic acids encoding these antibodies, vectors, and host cells are also provided. The disclosed antibodies, antigen binding fragments, nucleic acids and vectors can be used, for example, to inhibit an ebolavirus infection in a subject.