The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 07, 2024

Filed:

Apr. 28, 2021
Applicant:

Gilead Sciences, Inc., Foster City, CA (US);

Inventors:

Eda Y. Canales, San Mateo, CA (US);

Weng K. Chang, San Lorenzo, CA (US);

Laurent P. Debien, San Francisco, CA (US);

Petr Jansa, Foster City, CA (US);

Jennifer A. Loyer-Drew, Seattle, WA (US);

Luisruben P. Martinez, San Mateo, CA (US);

Stephane Perreault, Brier, WA (US);

Gary B Phillips, Issaquah, WA (US);

Hyung-Jung Pyun, Fremont, CA (US);

Roland D. Saito, San Mateo, CA (US);

Michael S. Sangi, San Mateo, CA (US);

Adam J. Schrier, Redwood City, CA (US);

Marina E. Shatskikh, San Francisco, CA (US);

James G. Taylor, Burlingame, CA (US);

Jennifer A. Treiberg, Redmond, WA (US);

Joshua J. Van Veldhuizen, Seattle, WA (US);

Assignee:

Gilead Sciences, Inc., Foster City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/18 (2006.01); A61K 31/4184 (2006.01); A61K 31/4188 (2006.01); A61K 31/437 (2006.01); A61K 45/06 (2006.01); A61P 3/10 (2006.01); A61P 7/02 (2006.01); A61P 19/02 (2006.01); A61P 35/00 (2006.01); C07D 471/12 (2006.01); C07D 471/14 (2006.01); C07D 487/08 (2006.01); C07D 491/22 (2006.01); C07D 498/18 (2006.01); C07D 498/22 (2006.01); C07D 513/18 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61K 45/06 (2013.01); C07D 471/14 (2013.01);
Abstract

The present disclosure relates to novel compounds for use in therapeutic treatment of a disease associated with peptidylarginine deiminases (PADs), such as peptidylarginine deiminase type 4 (PAD4). The present disclosure also relates to processes and intermediates for the preparation of such compounds, methods of using such compounds and pharmaceutical compositions comprising the compounds described herein.


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