The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2024
Filed:
Aug. 18, 2022
Applicants:
Nurix Therapeutics, Inc., San Francisco, CA (US);
Gilead Sciences, Inc., Foster City, CA (US);
Inventors:
Wylie Palmer, San Francisco, CA (US);
Jeffrey Wu, San Francisco, CA (US);
John Lee, San Francisco, CA (US);
Kerem Ozboya, San Francisco, CA (US);
Tim Kane, San Francisco, CA (US);
Assignee:
Gilead Sciences, Inc., Foster City, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5025 (2006.01); C07D 237/26 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 519/00 (2013.01);
Abstract
The present disclosure provides bifunctional compounds of Formula (I), and pharmaceutically acceptable salts, isotopic forms, isolated stereoisomers, or mixtures of stereoisomers thereof, as IRAK4 degraders via ubiquitin proteasome pathway, and method for treating diseases modulated by IRAK4.