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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11976067 B1

PDFFull Text
Date of Patent:
May. 07, 2024

Filed:

Jan. 17, 2023

Apol1 inhibitors and methods of use

Applicant:

Maze Therapeutics, Inc., South San Francisco, CA (US);

Inventors:

Patrick Sang Tae Lee, Walnut Creek, CA (US);

Todd Jonathan August Ewing, Walnut Creek, CA (US);

Adam Neil Reid, San Francisco, CA (US);

Christopher Joseph Sinz, Walnut Creek, CA (US);

Birong Zhang, Union City, CA (US);

Sarah M. Bronner, Oakland, CA (US);

David John Morgans, Jr., Los Altos, CA (US);

Maarten Hoek, Belmont, CA (US);

Victoria Anne Assimon, San Francisco, CA (US);

Chris Ziebenhaus, San Francisco, CA (US);

Alexander Wayne Schammel, San Diego, CA (US);

Assignee:

Maze Therapeutics, Inc., South San Francisco, CA (US);

Attorney:

MORRISON & FOERSTER LLP

Primary Examiner:

Charanjit Aulakh

Int. Cl.
CPC ...
C07D 471/10 (2006.01); A61K 31/438 (2006.01); C07D 487/10 (2006.01); C07D 519/00 (2006.01); C07F 9/53 (2006.01);
U.S. Cl.
CPC ...
C07D 471/10 (2013.01); C07D 487/10 (2013.01); C07D 519/00 (2013.01); C07F 9/5333 (2013.01); C07B 2200/05 (2013.01);
Abstract

Provided herein are compounds of formula (II): or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein m, n, p, R, R, R, L, L, L, R, X, X, X, and Xare as defined herein. Also provided are methods of preparing compounds of formula (II), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing. Also provided are methods of inhibiting APOL1 and methods of treating an APOL1-mediated disease, disorder, or condition in an individual.

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Quick Actions:

Lee, Patrick Sang Tae. (2024). Apol1 inhibitors and methods of use (U.S. Patent No. 11976067). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11976067

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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