The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2024
Filed:
Jan. 17, 2023
Maze Therapeutics, Inc., South San Francisco, CA (US);
Patrick Sang Tae Lee, Walnut Creek, CA (US);
Todd Jonathan August Ewing, Walnut Creek, CA (US);
Adam Neil Reid, San Francisco, CA (US);
Christopher Joseph Sinz, Walnut Creek, CA (US);
Birong Zhang, Union City, CA (US);
Sarah M. Bronner, Oakland, CA (US);
David John Morgans, Jr., Los Altos, CA (US);
Maarten Hoek, Belmont, CA (US);
Victoria Anne Assimon, San Francisco, CA (US);
Chris Ziebenhaus, San Francisco, CA (US);
Alexander Wayne Schammel, San Diego, CA (US);
Maze Therapeutics, Inc., South San Francisco, CA (US);
Abstract
Provided herein are compounds of formula (II): or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein m, n, p, R, R, R, L, L, L, R, X, X, X, and Xare as defined herein. Also provided are methods of preparing compounds of formula (II), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing. Also provided are methods of inhibiting APOL1 and methods of treating an APOL1-mediated disease, disorder, or condition in an individual.