The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 07, 2024

Filed:

Sep. 29, 2021
Applicant:

Merck Sharp & Dohme Llc, Rahway, NJ (US);

Inventors:

Luke R. Schenck, Yardley, PA (US);

David J. Lamberto, Jackson, NJ (US);

Joseph L. Kukura, II, Clark, NJ (US);

Francisco J. Guzman, Jersey City, NJ (US);

Aaron Cote, West Windsor, NJ (US);

Athanas Koynov, Highland Park, NJ (US);

Assignee:

Merck Sharp & Dohme LLC, Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 9/51 (2006.01);
U.S. Cl.
CPC ...
A61K 9/145 (2013.01); A61K 9/146 (2013.01); A61K 9/5123 (2013.01); A61K 9/5138 (2013.01); A61K 9/5146 (2013.01); A61K 9/5161 (2013.01);
Abstract

A process for preparing and isolating pharmaceutical active ingredient particles having a particle size of between about 0.1 and 30 microns, wherein a slurry comprising the active ingredient and one or more pharmaceutically acceptable excipients is fed into a thin film evaporator under suitable conditions for less than 10 minutes sufficient to generate solid matrix particles comprising active ingredient and one or more excipients, wherein the particles have less than 5% residual solvent.


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