The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2024
Filed:
Mar. 15, 2019
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventors:
Thomas J. Gardella, Needham, MA (US);
Ashok Khatri, Charlestown, MA (US);
Hiroshi Noda, Boston, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/29 (2006.01); A61K 47/54 (2017.01); A61K 47/65 (2017.01); C07K 14/635 (2006.01);
U.S. Cl.
CPC ...
A61K 38/29 (2013.01); A61K 47/542 (2017.08); A61K 47/65 (2017.08); C07K 14/635 (2013.01);
Abstract
Disclosed are peptide-fatty acid conjugates, pharmaceutical compositions containing them, and methods of their medical use in the treatment of, e.g., a disease or condition associated with the PTHR1 signaling overactivity (e.g., hypercalcemia, hypophosphatemia, hyperparathyroidism, or Jansen's chondrodysplasia) or deficiency (e.g., hypoparathyroidism, hyperphosphatemia, osteoporosis, fracture repair, osteomalacia, arthritis, or thrombocytopenia).