logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11974969 B1

PDFFull Text
Date of Patent:
May. 07, 2024

Filed:

Mar. 29, 2019

Artificially synthesized sphingosine derivative lipoid monomer and use of same for delivering nucleic acid

Applicant:

Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Beijing, CN;

Inventors:

Chengyu Jiang, Beijing, CN;

Yuhao Qin, Beijing, CN;

Xiaoyun Li, Beijing, CN;

Cong Zhang, Beijing, CN;

Assignee:

INSTITUTE OF BASIC MEDICAL SCIENCES CHINESE ACADEMY OF MEDICAL SCIENCES, Beijing, CN;

Attorneys:

Jun He Law Offices P.C.

Zhaohui Wang

Primary Examiner:

Brandon J Fetterolf

Assistant Examiner:

Lauren Wells

Int. Cl.
CPC ...
A61K 31/133 (2006.01); A61K 9/00 (2006.01); A61K 31/14 (2006.01); A61K 31/661 (2006.01); A61K 31/7016 (2006.01); A61K 31/702 (2006.01); A61K 47/18 (2017.01); A61K 47/24 (2006.01); A61P 35/00 (2006.01); C07C 69/003 (2006.01); C07C 69/587 (2006.01); C07C 215/10 (2006.01); C07C 233/18 (2006.01); C07F 9/10 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 31/133 (2013.01); A61K 9/0053 (2013.01); A61K 31/14 (2013.01); A61K 31/661 (2013.01); A61K 31/7016 (2013.01); A61K 31/702 (2013.01); A61K 47/18 (2013.01); A61K 47/24 (2013.01); A61P 35/00 (2018.01); C07C 69/003 (2013.01); C07C 69/587 (2013.01); C07C 215/10 (2013.01); C07C 233/18 (2013.01); C07F 9/10 (2013.01); C12N 15/113 (2013.01); C12N 2310/141 (2013.01); C12N 2320/32 (2013.01);
Abstract

The invention provides an artificially synthesized single sphingosine lipid and use of delivering a nucleic acid thereof. More particularly, the invention provides Use or method for delivering a nucleic acid to a cell or a subject using a compound of Formula (I), a stereoisomer or a pharmaceutical acceptable salt thereof, or a combination comprising a compound of Formula (I), a stereoisomer or a pharmaceutical acceptable salt thereof,

Find Patent Forward Citations

Loading…