The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2024
Filed:
Jun. 25, 2018
Applicant:
Children's Medical Center Corporation, Boston, MA (US);
Inventors:
Frederick W. Alt, Cambridge, MA (US);
Hwei-Ling Cheng, Northborough, MA (US);
Ming Tian, Boston, MA (US);
Assignee:
CHILDREN'S MEDICAL CENTER CORPORATION, Boston, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01K 67/0278 (2024.01); A01K 67/0271 (2024.01); C07K 16/00 (2006.01); C07K 16/10 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0278 (2013.01); A01K 67/0271 (2013.01); C07K 16/00 (2013.01); C07K 16/1045 (2013.01); C12N 15/8509 (2013.01); A01K 2207/12 (2013.01); A01K 2207/15 (2013.01); A01K 2217/052 (2013.01); A01K 2217/054 (2013.01); A01K 2217/072 (2013.01); A01K 2217/15 (2013.01); A01K 2227/105 (2013.01); A01K 2267/01 (2013.01); A01K 2267/03 (2013.01); C07K 2317/14 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/51 (2013.01); C07K 2317/56 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C12N 2015/8518 (2013.01); C12N 2015/8527 (2013.01); C12N 2800/30 (2013.01);
Abstract
Described herein are compositions (e.g. cells and transgenic animals) and methods relating to engineered Ig loci that permit expression of particular antibodies or antibody segments while still permitting recombination and/or maturation process for antibody optimization.