The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2024
Filed:
Aug. 02, 2019
Applicant:
The University of Toledo, Toledo, OH (US);
Inventors:
Shahnawaz Imam, Toledo, OH (US);
Maria Alfonso-Jaume, Toledo, OH (US);
Juan Carlos Jaume, Toledo, OH (US);
Assignee:
The University of Toledo, Toledo, OH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2024.01); A01K 67/0275 (2024.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0275 (2013.01); A61K 49/0008 (2013.01); A01K 2217/05 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0362 (2013.01);
Abstract
A mouse model that develops type 1 diabetes spontaneously and used thereof are described. In some embodiments, the mouse model expresses a combination of HLA-DQ8 and GAD65 in a C57BL/6-BTBR congenic background, where the GAD65 is expressed under the rat insulin promoter.