The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2024

Filed:

Apr. 03, 2020
Applicant:

Stellenbosch University, Stellenbosch, ZA;

Inventors:

Benjamin Loos, Cape Town, ZA;

Thomas Richard Niesler, Stellenbosch, ZA;

Rensu Petrus Theart, Stellenbosch, ZA;

Assignee:

STELLENBOSCH UNIVERSITY, Stellenbosch, ZA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G06T 19/20 (2011.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
G06T 19/20 (2013.01); G01N 21/6458 (2013.01); G06T 2219/2012 (2013.01);
Abstract

A computer-implemented method and a system are provided for visualising colocalised fluorescence signals. The method accesses signal intensity data obtained from a first fluorescence channel and a second fluorescence channel in which the signal intensity data is associated with voxels in an image. A regression factor on the signal intensity data is calculated to generate a regression parameter corresponding to a degree of correlation between the signal intensity data obtained from the first and second fluorescence channels The signal intensity data is mapped to the regression parameter and colourmap values are assigned to each voxel based on the mapped signal intensity data in which colourmap values of voxels embodying poorly correlated signal intensity data are reduced. The method renders the voxels in the image in colours according to their colourmap values to visualise colocalisation in the image.


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