The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2024
Filed:
Jan. 20, 2017
Dana-farber Cancer Institute, Inc., Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Curtis Huttenhower, Boston, MA (US);
Travis Gerke, Tampa, FL (US);
Christopher Sweeney, Waban, MA (US);
Lorelei Mucci, Newton, MA (US);
Gwo-Sho Mary Lee, Newton, MA (US);
Daniela Bornigen, Tostedt, DE;
Xiaodong Wang, Stoughton, MA (US);
Svitlana Tyekucheva, Boston, MA (US);
Kristina Jordahl, Seattle, WA (US);
DANA-FARBER CANCER INSTITUTE, INC., Boston, MA (US);
PRESIDENT AND FELLOWS OF HARVARD COLLEGE, Cambridge, MA (US);
Abstract
The present invention provides methods for screening and diagnosing prostate cancer based on a correlation between cancer cell growth, cancer lethality or recurrence and the expression level of ZFP36 or NEDD9 and PTEN in conjunction with ZFP36. The disclosure also provides methods for screening and diagnosing prostate cancer based on a correlation between cancer lethality and the genotype of rs1910301 SNP. Also provided are methods for treating prostate cancer comprising providing a treatment or monitoring based on the expression level of ZFP36, the expression level of NEDD9, and the expression level of ZFP36 in conjunction with PTEN levels or the genotype of rs1910301 SNP.