The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2024

Filed:

Apr. 27, 2022
Applicant:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Inventors:

Herbert Andres, Penzberg, DE;

Johann Karl, Peissenberg, DE;

Ursula Kunert, Munich, DE;

David Morgenstern, Indianapolis, IN (US);

Nina Meissler, Huglfing, DE;

Marion Niessner, Penzberg, DE;

Magdalena Swiatek-de Lange, Penzberg, DE;

Assignee:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C07K 16/46 (2006.01); G01N 33/564 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
G01N 33/564 (2013.01); C07K 16/46 (2013.01); G01N 33/574 (2013.01); G01N 33/5748 (2013.01); G01N 33/57496 (2013.01);
Abstract

An in vitro method is disclosed for detecting an antibody to p53 (anti-p53 antibody) in a sample, the method comprising: incubating a sample to be analyzed with a p53 capture antigen and a p53 detection antigen, whereby a complex comprising the p53 capture antigen, the anti-p53 antibody and the p53 detection antigen is formed, separating the complex formed from unbound detection antigen and measuring the complex obtained via the detection antigen comprised therein, thereby detecting the anti-p53 antibody comprised in the sample.


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