The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2024
Filed:
Oct. 18, 2021
Applicant:
Twist Bioscience Corporation, South San Francisco, CA (US);
Inventors:
Jeremy Lackey, Foster City, CA (US);
David Dodd, San Francisco, CA (US);
Assignee:
Twist Bioscience Corporation, South San Franciso, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/1093 (2013.01); C12N 15/102 (2013.01); C12N 15/113 (2013.01); C12N 2310/315 (2013.01); C12N 2320/33 (2013.01);
Abstract
Disclosed herein are methods and compositions comprising a polymerase and a phosphorylated nucleoside, wherein the polymerase and the nucleoside are covalently linked by a cleavable linker at the terminal phosphate group. Further disclosed herein are enzymatic polynucleotide synthesis using polymerase and nucleotide conjugation strategies.