The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2024
Filed:
Aug. 23, 2022
Applicants:
Innovative Cellular Therapeutics Holdings, Ltd., George Town, KY;
Innovative Cellular Therapeutics, Inc., Rockville, MD (US);
Inventors:
Zhiyuan Cao, Shanghai, CN;
Yuzhe Peng, Shanghai, CN;
Lei Xiao, Rockville, MD (US);
Zhao Wu, Shanghai, CN;
Le Tian, Rockville, MD (US);
Assignees:
Innovative Cellular Therapeutics Holdings, Ltd., George Town, KY;
Innovative Cellular Therapeutics, Inc., Rockville, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 21/08 (2006.01); A61K 35/17 (2015.01); A61K 39/395 (2006.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01); C07K 14/725 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); C07K 16/40 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 35/17 (2013.01); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); A61K 38/00 (2013.01); C07K 2317/56 (2013.01); C12Y 406/01002 (2013.01);
Abstract
The compositions and methods described herein are directed to treating solid tumors using CAR T therapy and/or antibodies targeting GCC. The compositions include CAR comprising an extracellular domain that binds GCC.