The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2024
Filed:
May. 20, 2021
Compass Therapeutics Llc, Brighton, MA (US);
Bing Gong, Brighton, MA (US);
Rachel Rennard, Stoneham, MA (US);
Amanda Frank Oliphant, Boston, MA (US);
Cheuk Lun Leung, Quincy, MA (US);
Benjamin Jacob Wolf, Seattle, WA (US);
Ugur Eskiocak, Somerville, MA (US);
Pearl Bakhru, Ashland, MA (US);
Diana I. Albu, Windham, NH (US);
COMPASS THERAPEUTICS LLC, Brighton, MA (US);
Abstract
The present disclosure relates to compositions and methods for inhibiting tumor evasion by reducing immune checkpoint suppression. In some embodiments, provided herein are compositions that block the interaction between PD-1 and its ligand (e.g., PD-1 and/or PD-L2) while promoting the interaction of the cells on which PD-1 and its ligand are expressed. Also provided are methods of using such compositions.