The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2024

Filed:

Dec. 10, 2018
Applicant:

Sichuan Kelun-biotech Biopharmaceutical Co., Ltd., Chengdu, CN;

Inventors:

Jiaqiang Cai, Chengdu, CN;

Shuai Song, Chengdu, CN;

Tongtong Xue, Chengdu, CN;

Liang Xiao, Chengdu, CN;

Hanwen Deng, Chengdu, CN;

Qiang Tian, Chengdu, CN;

Guoqing Zhong, Chengdu, CN;

Lichun Wang, Chengdu, CN;

Jingyi Wang, Chengdu, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 491/22 (2006.01); A61K 45/06 (2006.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07K 5/062 (2006.01); C07K 16/30 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
C07D 491/22 (2013.01); A61K 47/6803 (2017.08); A61K 47/6851 (2017.08); A61K 47/6885 (2017.08); A61P 35/00 (2018.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07K 5/06052 (2013.01); C07K 16/30 (2013.01); C07K 16/32 (2013.01); A61K 45/06 (2013.01);
Abstract

Provided herein are bioactive molecule conjugates, preparation methods and use thereof, particularly bioactive molecule conjugates (such as antibody-drug conjugates and small molecule drug conjugates) obtained by improved coupling of a drug and a targeting moiety, as well as their preparation method and use for the treatment of a disease associated with an abnormal cell activity.


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