The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2024
Filed:
Jul. 31, 2020
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Chris Adair, Brighton, MA (US);
Tracy Chen, Litchfield, NH (US);
Jian Ding, Bedford, MA (US);
Christy Fryer, Cambridge, MA (US);
Yuko Isome, Arlington, MA (US);
Marie-Helene Larraufie, Barcelona, ES;
Katsumasa Nakajima, Winchester, MA (US);
Nik Savage, Somerville, MA (US);
Ariel Sterling Twomey, Everett, MA (US);
Assignee:
Novartis AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/10 (2006.01); A61P 35/00 (2006.01); A61K 31/4747 (2006.01);
U.S. Cl.
CPC ...
C07D 471/10 (2013.01); A61P 35/00 (2018.01); A61K 31/4747 (2013.01);
Abstract
The present invention relates to novel tricyclic compounds that are AKR1C3 dependent KARS inhibitor, processes for their preparation, pharmaceutical compositions, and medicaments containing them, and their use in diseases and disorders mediated by an AKR1C3 dependent KARS inhibitor.