The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2024

Filed:

Mar. 25, 2021
Applicants:

Risen (Suzhou) Pharma Tech Co., Ltd., Jiangsu, CN;

Shanghai Junshi Biosciences Co., Ltd., Shanghai, CN;

Inventors:

Jiasheng Lu, Shanghai, CN;

Jiamin Gu, Suzhou, CN;

Xiang Ji, Suzhou, CN;

Dongqing Zhu, Suzhou, CN;

Xiaolin He, Suzhou, CN;

Xianqi Kong, Dollard-des-Ormeaux, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/14 (2006.01); A61K 31/565 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); A61K 31/565 (2013.01); C07B 59/002 (2013.01); C07B 2200/05 (2013.01);
Abstract

There are provided isotope-enriched compounds containing stable heavy isotope-enriched amide functional groups for modulating the pharmacokinetic profile, metabolic profile, and/or delivery efficiency of a drug or prodrug, as well as its therapeutic or prophylactic efficacy and/or adverse effects. Use of the isotope-enriched amide-containing drugs and prodrugs for the treatment or prevention of disease states and conditions is also provided.


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